Size before and after Tissue Fixation: A Comparison of Haloperidol and
Olanzapine in Macaque Monkeys
http://www.nature.com/npp/journal/v30/n9/abs/1300710a.html
This would disturb anyone with schizophrenia who happily accepts their
drug treatment and also anyone who likes monkeys..
"Three groups of six macaque monkeys each were exposed to oral
haloperidol, olanzapine or sham for a 17–27 month period. The resulting
plasma drug levels were comparable to those seen in subjects with
schizophrenia treated with these medications. After the exposure, we
observed an 8–11% reduction in mean fresh brain weights as well as left
cerebrum fresh weights and volumes in both drug-treated groups compared
to sham animals. The differences were observed across all major brain
regions (frontal, parietal, temporal, occipital, and cerebellum), but
appeared most robust in the frontal and parietal regions. "
Anyone who knows the history of antipsychotics knows when they were
first introduced they were described as a chemical lobotomy. This was
because they created the same effect without carving out a person's
brain. Clearly they are actually damaging people's brains after all.
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